Peptide Half-Life Guide

Quick half-life reference for peptides in our library.

Use this to compare approximate elimination windows and dosing cadence context. Half-life values vary by formulation and source data.

42 peptides with listed half-life data

PeptideHalf-Life
AOD-9604~30 minutes
BPC-157~4 hours
Cerebrolysin~3 hours (peptide fractions)
CJC-12956–8 days (with DAC)
CJC-1295 (no DAC)~30 minutes
DihexaUnknown (limited human pharmacokinetic data)
DSIP~30 minutes
Epithalon~3 hours (estimated)
Follistatin 344~35 hours
FOXO4-DRIUnknown (D-amino acid resistance to proteolysis extends activity)
GHK-Cu~30 minutes (plasma)
GHRP-2~30 minutes
GHRP-615–60 minutes
Gonadorelin~2–10 minutes
Hexarelin~70 minutes
HGH (Somatropin)~2-3 hours (biologic effects extend via IGF-1)
Humanin~3 hours (estimated)
IGF-1 LR320–30 hours
Ipamorelin~2 hours
Kisspeptin~28 minutes
KPV~1 hour (estimated)
Liraglutide~13 hours
LL-37~1 hour (estimated)
Melanotan II~33 minutes
MK-677~24 hours
Mod GRF 1-29~30 minutes
MOTS-c~1 hour (estimated)
NAD+~minutes (IV NAD+); precursor molecules (NMN, NR) have longer stability
Oxytocin~3–5 minutes (IV); ~90 minutes (intranasal CNS effect)
PEG-MGF~5 days (PEGylated form)
PT-141~2.7 hours
Retatrutide~6 days
Selank~3 minutes (intranasal, active)
Semaglutide~7 days
Semax~7 minutes (active fragment in plasma)
Sermorelin~11 minutes
SS-31~1.5 hours
TB-500~3 days
Tesamorelin~26 minutes
Thymosin Alpha-1~2 hours
Tirzepatide5 days
VIP~1–2 minutes (plasma)

Educational only, not medical advice. Always verify product-specific kinetics from labeling, prescribing information, and primary clinical literature.