PubMed
Randomized controlled trial of oral glutathione supplementation on body stores of glutathione
Richie et al., 2015
GSH
Endogenous tripeptide antioxidant used across wellness and clinical protocols.
Trend index
Overview
Endogenous tripeptide antioxidant used across wellness and clinical protocols.
Community
Positive 98% · Neutral 2% · Negative 0%
Median: 2000+ mcg · Most common: 2000+ mcg
Among repeat reporters, 96% said they felt similar to their last entry, 4% more positive, and 0% more negative.
Overall, repeat reporters leaned more positive than their previous entry.
Median gap between entries: 66 days · Based on 26 repeat reporters
Research
PubMed
Richie et al., 2015
PubMed
Davids et al., 2016
Help
This page summarizes 37 anonymized self-reports from PeptIQ users who track Glutathione, including commonly reported effects and co-tracked peptides. These are observational patterns, not clinical outcomes.
2 sources are linked on this page, including PubMed articles, clinical trial registries, and FDA labels where applicable. Citations describe published research — not recommendations.
This wiki does not assess safety or recommend use. Glutathione is listed as Clinical / Compoundable. Consult a licensed clinician for personal medical decisions.
Research, primarily in animal models, suggests Glutathione may have a wide range of therapeutic potentials due to its ability to promote angiogenesis (formation of new blood vessels), stimulate collagen synthesis, and modulate inflammatory responses.
SourceGlutathione is not approved by the FDA for any human use. There is no legal basis for selling it as a drug, food, or dietary supplement in the United States. The FDA has classified Glutathione as a Category 2 bulk drug substance, which explicitly prohibits licensed compounding pharmacies from using it in compounded medications.
SourceThe safety and effectiveness of Glutathione have not been thoroughly evaluated in humans through rigorous clinical trials. This lack of human data means that safe dosages, short-term side effects, and long-term health consequences are largely unknown.
SourceWhile there are over 200 published studies on Glutathione, the vast majority are animal or in vitro (cell) studies. These preclinical studies consistently show positive results across various tissue types. However, there is a significant lack of comprehensive human clinical trial data.
Source