PubMed
Stable gastric pentadecapeptide BPC 157: Novel therapy in gastrointestinal tract
Sikiric et al., 2018
Healing & RecoveryResearch OnlyS
BPC-157
Pentadecapeptide BPC 157
BPC-157 is a synthetic pentadecapeptide (15 amino acids) derived from a gastric juice protein, researched extensively for accelerating tissue healing, gut repair, and tendon recovery. Animal studies demonstrate dose-dependent healing of tendons, ligaments, bones, muscles, and intestinal tissue, along with anti-inflammatory and angiogenic effects. Not FDA-approved; placed on the FDA's 503A prohibited bulk substances list in 2023.
Observational report only — live community data. Not medical advice. Does not recommend doses, protocols, or treatments.
- Studies cited
- 5
- Research grade
- S
- Community score
- 152
- Trackers
- 2,515
Trend index
Overview
About BPC-157
BPC-157 is a synthetic pentadecapeptide (15 amino acids) derived from a gastric juice protein, researched extensively for accelerating tissue healing, gut repair, and tendon recovery. Animal studies demonstrate dose-dependent healing of tendons, ligaments, bones, muscles, and intestinal tissue, along with anti-inflammatory and angiogenic effects. Not FDA-approved; placed on the FDA's 503A prohibited bulk substances list in 2023.
- Category
- Healing & Recovery
- Regulatory status
- Research Only
- Also known as
- Pentadecapeptide BPC 157
- Self-reports
- 126
Community
What 126 users report
126 community reports
Positive 98% · Neutral 2% · Negative 0%
Most reported benefits
Recovery
245
Most reported side effects
Nausea
5
Dose distribution
Median: 200–400 mcg · Most common: 200–400 mcg
0–25
2
25–50
1
50–100
0
100–200
3
200–400
138
400–600
93
600–1000
5
1000–2000
1
2000+
2
Commonly stacked with
How repeat users are trending
Among repeat reporters, 94% said they felt similar to their last entry, 6% more positive, and 0% more negative.
Overall, repeat reporters leaned more positive than their previous entry.
Median gap between entries: 50 days · Based on 47 repeat reporters
Research
Cited research (3)
Source
PubMed
Pentadecapeptide BPC 157 enhances the growth hormone receptor expression in tendon fibroblasts
Chang et al., 2019
PubMed
BPC 157 and its role in accelerating wound healing
Vukojevic et al., 2022
Help
Frequently asked
What do PeptIQ users report about BPC-157?
This page summarizes 126 anonymized self-reports from PeptIQ users who track BPC-157, including commonly reported effects and co-tracked peptides. These are observational patterns, not clinical outcomes.
What research is cited for BPC-157?
3 sources are linked on this page, including PubMed articles, clinical trial registries, and FDA labels where applicable. Citations describe published research — not recommendations.
Is BPC-157 safe to use?
This wiki does not assess safety or recommend use. BPC-157 is listed as Research Only. Consult a licensed clinician for personal medical decisions.
What are the purported benefits and uses of BPC-157?
Research, primarily in animal models, suggests BPC-157 may have a wide range of therapeutic potentials due to its ability to promote angiogenesis (formation of new blood vessels), stimulate collagen synthesis, and modulate inflammatory responses.
SourceWhat is the legal status of BPC-157?
BPC-157 is not approved by the FDA for any human use. There is no legal basis for selling it as a drug, food, or dietary supplement in the United States. The FDA has classified BPC-157 as a Category 2 bulk drug substance, which explicitly prohibits licensed compounding pharmacies from using it in compounded medications.
SourceWhat are the known or theoretical side effects and risks of BPC-157?
The safety and effectiveness of BPC-157 have not been thoroughly evaluated in humans through rigorous clinical trials. This lack of human data means that safe dosages, short-term side effects, and long-term health consequences are largely unknown.
SourceWhat is the current state of research on BPC-157?
While there are over 200 published studies on BPC-157, the vast majority are animal or in vitro (cell) studies. These preclinical studies consistently show positive results across various tissue types. However, there is a significant lack of comprehensive human clinical trial data.
Source