PubMed
The effect of (L-)carnitine on weight loss in adults: a systematic review and meta-analysis of randomized controlled trials
Pooyandjoo et al., 2016
Longevity & Anti-AgingSupplement / Rx formsS
L-Carnitine
Levocarnitine
Amino-acid derivative used for mitochondrial and metabolic support (non-peptide).
Observational report only — live community data. Not medical advice. Does not recommend doses, protocols, or treatments.
- Studies cited
- 4
- Research grade
- S
- Community score
- 82
- Trackers
- 1,298
Trend index
Overview
About L-Carnitine
Amino-acid derivative used for mitochondrial and metabolic support (non-peptide).
- Category
- Longevity & Anti-Aging
- Regulatory status
- Supplement / Rx forms
- Also known as
- Levocarnitine
- Self-reports
- 25
Community
What 25 users report
25 community reports
Positive 97% · Neutral 3% · Negative 0%
Most reported benefits
Appetite
152
Most reported side effects
Nausea
5
Dose distribution
Median: 2000+ mcg · Most common: 2000+ mcg
0–25
0
25–50
0
50–100
0
100–200
0
200–400
3
400–600
2
600–1000
0
1000–2000
0
2000+
147
Commonly stacked with
How repeat users are trending
Among repeat reporters, 84% said they felt similar to their last entry, 16% more positive, and 0% more negative.
Overall, repeat reporters leaned more positive than their previous entry.
Median gap between entries: 119 days · Based on 25 repeat reporters
Research
Cited research (3)
Source
PubMed
Randomised clinical trial: the efficacy and safety of propionyl-L-carnitine therapy in patients with ulcerative colitis receiving stable oral treatment
Mikhailova et al., 2011
ClinicalTrials.gov
Propionyl-L-Carnitine in Ulcerative Colitis (NCT01026857)
ClinicalTrials.gov, 2009
Help
Frequently asked
What do PeptIQ users report about L-Carnitine?
This page summarizes 25 anonymized self-reports from PeptIQ users who track L-Carnitine, including commonly reported effects and co-tracked peptides. These are observational patterns, not clinical outcomes.
What research is cited for L-Carnitine?
3 sources are linked on this page, including PubMed articles, clinical trial registries, and FDA labels where applicable. Citations describe published research — not recommendations.
Is L-Carnitine safe to use?
This wiki does not assess safety or recommend use. L-Carnitine is listed as Supplement / Rx forms. Consult a licensed clinician for personal medical decisions.
What are the purported benefits and uses of L-Carnitine?
Research, primarily in animal models, suggests L-Carnitine may have a wide range of therapeutic potentials due to its ability to promote angiogenesis (formation of new blood vessels), stimulate collagen synthesis, and modulate inflammatory responses.
SourceWhat is the legal status of L-Carnitine?
L-Carnitine is not approved by the FDA for any human use. There is no legal basis for selling it as a drug, food, or dietary supplement in the United States. The FDA has classified L-Carnitine as a Category 2 bulk drug substance, which explicitly prohibits licensed compounding pharmacies from using it in compounded medications.
SourceWhat are the known or theoretical side effects and risks of L-Carnitine?
The safety and effectiveness of L-Carnitine have not been thoroughly evaluated in humans through rigorous clinical trials. This lack of human data means that safe dosages, short-term side effects, and long-term health consequences are largely unknown.
SourceWhat is the current state of research on L-Carnitine?
While there are over 200 published studies on L-Carnitine, the vast majority are animal or in vitro (cell) studies. These preclinical studies consistently show positive results across various tissue types. However, there is a significant lack of comprehensive human clinical trial data.
Source