PubMed
Phase Ib dose-escalation study of the hypoxia-modifier Myo-inositol trispyrophosphate in patients with hepatopancreatobiliary tumors
Schneider et al., 2021
Myo-inositol trispyrophosphate
Experimental oxygen-delivery/metabolic performance compound tracked in research circles.
Trend index
Overview
Experimental oxygen-delivery/metabolic performance compound tracked in research circles.
Community
Positive 97% · Neutral 3% · Negative 0%
Median: 2000+ mcg · Most common: 2000+ mcg
Among repeat reporters, 90% said they felt similar to their last entry, 10% more positive, and 0% more negative.
Overall, repeat reporters leaned more positive than their previous entry.
Median gap between entries: 163 days · Based on 20 repeat reporters
Research
PubMed
Schneider et al., 2021
ClinicalTrials.gov
ClinicalTrials.gov, 2015
Help
This page summarizes 21 anonymized self-reports from PeptIQ users who track ITPP, including commonly reported effects and co-tracked peptides. These are observational patterns, not clinical outcomes.
2 sources are linked on this page, including PubMed articles, clinical trial registries, and FDA labels where applicable. Citations describe published research — not recommendations.
This wiki does not assess safety or recommend use. ITPP is listed as Research Only. Consult a licensed clinician for personal medical decisions.
Research, primarily in animal models, suggests ITPP may have a wide range of therapeutic potentials due to its ability to promote angiogenesis (formation of new blood vessels), stimulate collagen synthesis, and modulate inflammatory responses.
SourceITPP is not approved by the FDA for any human use. There is no legal basis for selling it as a drug, food, or dietary supplement in the United States. The FDA has classified ITPP as a Category 2 bulk drug substance, which explicitly prohibits licensed compounding pharmacies from using it in compounded medications.
SourceThe safety and effectiveness of ITPP have not been thoroughly evaluated in humans through rigorous clinical trials. This lack of human data means that safe dosages, short-term side effects, and long-term health consequences are largely unknown.
SourceWhile there are over 200 published studies on ITPP, the vast majority are animal or in vitro (cell) studies. These preclinical studies consistently show positive results across various tissue types. However, there is a significant lack of comprehensive human clinical trial data.
Source