PubMed
Evaluation and treatment of adult growth hormone deficiency: an Endocrine Society clinical practice guideline
Molitch et al., 2011
Human Growth Hormone / rhGH
Human Growth Hormone (somatropin, rhGH) is a recombinant form of endogenous growth hormone used clinically for growth hormone deficiency and selected catabolic conditions. It remains one of the most studied anabolic endocrine therapies, with extensive evidence in pediatric and adult GHD populations and ongoing registry data for long-term outcomes. Off-label use for body composition and anti-aging remains medically controversial and should be physician-supervised.
Trend index
Overview
Human Growth Hormone (somatropin, rhGH) is a recombinant form of endogenous growth hormone used clinically for growth hormone deficiency and selected catabolic conditions. It remains one of the most studied anabolic endocrine therapies, with extensive evidence in pediatric and adult GHD populations and ongoing registry data for long-term outcomes. Off-label use for body composition and anti-aging remains medically controversial and should be physician-supervised.
Community
Positive 2% · Neutral 98% · Negative 0%
Median: 0–25 mcg · Most common: 0–25 mcg
Among repeat reporters, 88% said they felt similar to their last entry, 12% more positive, and 0% more negative.
Overall, repeat reporters leaned more positive than their previous entry.
Median gap between entries: 133 days · Based on 26 repeat reporters
Research
PubMed
Molitch et al., 2011
Help
This page summarizes 28 anonymized self-reports from PeptIQ users who track HGH (Somatropin), including commonly reported effects and co-tracked peptides. These are observational patterns, not clinical outcomes.
1 sources are linked on this page, including PubMed articles, clinical trial registries, and FDA labels where applicable. Citations describe published research — not recommendations.
This wiki does not assess safety or recommend use. HGH (Somatropin) is listed as FDA Approved (indication-specific). Consult a licensed clinician for personal medical decisions.
Research, primarily in animal models, suggests HGH (Somatropin) may have a wide range of therapeutic potentials due to its ability to promote angiogenesis (formation of new blood vessels), stimulate collagen synthesis, and modulate inflammatory responses.
SourceHGH (Somatropin) is not approved by the FDA for any human use. There is no legal basis for selling it as a drug, food, or dietary supplement in the United States. The FDA has classified HGH (Somatropin) as a Category 2 bulk drug substance, which explicitly prohibits licensed compounding pharmacies from using it in compounded medications.
SourceThe safety and effectiveness of HGH (Somatropin) have not been thoroughly evaluated in humans through rigorous clinical trials. This lack of human data means that safe dosages, short-term side effects, and long-term health consequences are largely unknown.
SourceWhile there are over 200 published studies on HGH (Somatropin), the vast majority are animal or in vitro (cell) studies. These preclinical studies consistently show positive results across various tissue types. However, there is a significant lack of comprehensive human clinical trial data.
Source