Compare

LL-37 vs Melanotan II

Side-by-side observational reports from PeptIQ users. This compares self-reported patterns — not clinical head-to-head trials.

Last reviewed . By the PeptIQ team.

Observational reporting only — not medical advice. Does not recommend doses, protocols, or treatments.

LL-37

6 community reports

Overall experience

From check-in ratings — separate from side effects logged below. Side effects are logged separately from overall experience. A favorable check-in can still include nausea, fatigue, or injection-site reactions.

Favorable 100% · Mixed 0% · Unfavorable overall 0%

Most reported benefits

Benefits users selected when logging a favorable or mixed check-in.

Recovery
6

Self-reported dose per injection

Median bucket: 100–200 mcg · Most common: 100–200 mcg

Reports span 100–400 mcg

100–200
4
200–400
2

Anonymized self-reports from PeptIQ users — not prescribing guidance. Buckets group similar logged amounts; open-ended top buckets mean “at least” that dose.

Commonly stacked with

Melanotan II

46 community reports

Overall experience

From check-in ratings — separate from side effects logged below. Side effects are logged separately from overall experience. A favorable check-in can still include nausea, fatigue, or injection-site reactions.

Favorable 97% · Mixed 3% · Unfavorable overall 0%

Most reported benefits

Benefits users selected when logging a favorable or mixed check-in.

Libido
142
Mood
141
Appetite
73

Most logged side effects

Side effects are logged separately from overall experience. A favorable check-in can still include nausea, fatigue, or injection-site reactions.

Fatigue
2
Nausea
2

Self-reported dose per injection

Median bucket: 0.4–0.6 mg · Most common: 0.2–0.4 mg

Reports span 0.01–2 mg

0.01–0.025 mg
1
0.05–0.1 mg
1
0.1–0.2 mg
7
0.2–0.4 mg
49
0.4–0.6 mg
23
0.6–1 mg
33
1–2 mg
28

Anonymized self-reports from PeptIQ users — not prescribing guidance. Buckets group similar logged amounts; open-ended top buckets mean “at least” that dose.

How repeat users are trending

Among repeat reporters, 94% said they felt similar to their last entry, 6% more positive, and 0% more negative.

Overall, repeat reporters leaned more positive than their previous entry.

Median gap between entries: 50 days · Based on 32 repeat reporters

Sources (8)

Published sources linked on the LL-37 and Melanotan II wiki pages.

  1. PubMed

    LL-37, the only human member of the cathelicidin family of antimicrobial peptides

    Vandamme D, Landuyt B, Luyten W, et al. Biochim Biophys Acta. 2012

    Source
    Wiki study page →
  2. PubMed

    The antimicrobial peptide LL-37 inhibits biofilm formation

    Dean SN, Bishop BM, van Hoek ML. BMC Microbiol. 2011

    Source
    Wiki study page →
  3. PubMed

    Rosacea: Pathogenesis and Therapeutic Correlates

    Geng RSQ, Bourkas AN, Mufti A, et al. Journal of cutaneous medicine and surgery. 2024

    Source
    Wiki study page →
  4. PubMed

    LL-37 antimicrobial peptide: Molecular characterisation and its role in oral health and disease-A narrative review

    Soman D, P J, Cm M, et al. Archives of oral biology. 2026

    Source
    Wiki study page →
  5. PubMed

    LC-HRMS characterization of the skin pigmentation and sexual enhancers melanotan II and bremelanotide sold on the black market of performance and image enhancing drugs

    Mestria S, Odoardi S, Frison G, et al. Drug testing and analysis. 2021

    Source
    Wiki study page →
  6. PubMed

    Melanotan II injection resulting in systemic toxicity and rhabdomyolysis

    Nelson ME, Bryant SM, Aks SE. Clinical toxicology (Philadelphia, Pa.). 2012

    Source
    Wiki study page →