PubMed
Hexarelin, a synthetic growth hormone-releasing peptide, vs GHRH in GH-deficient adults
Ghigo et al., 1996
Examorelin
Hexarelin (examorelin) is a synthetic hexapeptide GHRP with the highest GH-releasing potency among the GHRP class. Uniquely among GH secretagogues, hexarelin has demonstrated direct cardioprotective effects through CD36 receptor binding that are independent of GH release — making it of research interest for cardiac protection applications. Research use only; not FDA-approved.
Trend index
Overview
Hexarelin (examorelin) is a synthetic hexapeptide GHRP with the highest GH-releasing potency among the GHRP class. Uniquely among GH secretagogues, hexarelin has demonstrated direct cardioprotective effects through CD36 receptor binding that are independent of GH release — making it of research interest for cardiac protection applications. Research use only; not FDA-approved.
Community
Positive 97% · Neutral 3% · Negative 0%
Median: 100–200 mcg · Most common: 100–200 mcg
Among repeat reporters, 87% said they felt similar to their last entry, 13% more positive, and 0% more negative.
Overall, repeat reporters leaned more positive than their previous entry.
Median gap between entries: 148 days · Based on 23 repeat reporters
Research
PubMed
Ghigo et al., 1996
PubMed
Bisi et al., 2001
Help
This page summarizes 24 anonymized self-reports from PeptIQ users who track Hexarelin, including commonly reported effects and co-tracked peptides. These are observational patterns, not clinical outcomes.
2 sources are linked on this page, including PubMed articles, clinical trial registries, and FDA labels where applicable. Citations describe published research — not recommendations.
This wiki does not assess safety or recommend use. Hexarelin is listed as Research Only. Consult a licensed clinician for personal medical decisions.
Research, primarily in animal models, suggests Hexarelin may have a wide range of therapeutic potentials due to its ability to promote angiogenesis (formation of new blood vessels), stimulate collagen synthesis, and modulate inflammatory responses.
SourceHexarelin is not approved by the FDA for any human use. There is no legal basis for selling it as a drug, food, or dietary supplement in the United States. The FDA has classified Hexarelin as a Category 2 bulk drug substance, which explicitly prohibits licensed compounding pharmacies from using it in compounded medications.
SourceThe safety and effectiveness of Hexarelin have not been thoroughly evaluated in humans through rigorous clinical trials. This lack of human data means that safe dosages, short-term side effects, and long-term health consequences are largely unknown.
SourceWhile there are over 200 published studies on Hexarelin, the vast majority are animal or in vitro (cell) studies. These preclinical studies consistently show positive results across various tissue types. However, there is a significant lack of comprehensive human clinical trial data.
Source