GH SecretagoguesResearch OnlyS

GHRP-2

Pralmorelin

GHRP-2 (pralmorelin) is a synthetic hexapeptide GH secretagogue with stronger GH-releasing potency than GHRP-6 but with less pronounced appetite stimulation. Used in clinical research for GH deficiency diagnosis and studied for body composition effects. It is approved in Japan as a diagnostic agent for GH deficiency (Pralmorelin KM) but not approved for therapeutic use in the US.

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Observational report only — live community data. Not medical advice. Does not recommend doses, protocols, or treatments.
Studies cited
3
Research grade
S
Community score
185

Trend index

Trackers
3,708

Overview

About GHRP-2

GHRP-2 (pralmorelin) is a synthetic hexapeptide GH secretagogue with stronger GH-releasing potency than GHRP-6 but with less pronounced appetite stimulation. Used in clinical research for GH deficiency diagnosis and studied for body composition effects. It is approved in Japan as a diagnostic agent for GH deficiency (Pralmorelin KM) but not approved for therapeutic use in the US.

Category
GH Secretagogues
Regulatory status
Research Only
Also known as
Pralmorelin
Self-reports
26

Community

What 26 users report

26 community reports

Positive 3% · Neutral 3% · Negative 94%

Most reported benefits

Appetite
162
Sleep
10

Most reported side effects

Water retention
157

Dose distribution

Median: 200–400 mcg · Most common: 200–400 mcg

0–25
0
25–50
0
50–100
0
100–200
60
200–400
102
400–600
0
600–1000
0
1000–2000
0
2000+
0

How repeat users are trending

Among repeat reporters, 79% said they felt similar to their last entry, 21% more positive, and 0% more negative.

Overall, repeat reporters leaned more positive than their previous entry.

Median gap between entries: 180 days · Based on 24 repeat reporters

Research

Cited research (2)

Help

Frequently asked

What do PeptIQ users report about GHRP-2?

This page summarizes 26 anonymized self-reports from PeptIQ users who track GHRP-2, including commonly reported effects and co-tracked peptides. These are observational patterns, not clinical outcomes.

What research is cited for GHRP-2?

2 sources are linked on this page, including PubMed articles, clinical trial registries, and FDA labels where applicable. Citations describe published research — not recommendations.

Is GHRP-2 safe to use?

This wiki does not assess safety or recommend use. GHRP-2 is listed as Research Only. Consult a licensed clinician for personal medical decisions.

What are the purported benefits and uses of GHRP-2?

Research, primarily in animal models, suggests GHRP-2 may have a wide range of therapeutic potentials due to its ability to promote angiogenesis (formation of new blood vessels), stimulate collagen synthesis, and modulate inflammatory responses.

Source

What is the legal status of GHRP-2?

GHRP-2 is not approved by the FDA for any human use. There is no legal basis for selling it as a drug, food, or dietary supplement in the United States. The FDA has classified GHRP-2 as a Category 2 bulk drug substance, which explicitly prohibits licensed compounding pharmacies from using it in compounded medications.

Source

What are the known or theoretical side effects and risks of GHRP-2?

The safety and effectiveness of GHRP-2 have not been thoroughly evaluated in humans through rigorous clinical trials. This lack of human data means that safe dosages, short-term side effects, and long-term health consequences are largely unknown.

Source

What is the current state of research on GHRP-2?

While there are over 200 published studies on GHRP-2, the vast majority are animal or in vitro (cell) studies. These preclinical studies consistently show positive results across various tissue types. However, there is a significant lack of comprehensive human clinical trial data.

Source