Compare

LL-37 vs MK-677

Side-by-side observational reports from PeptIQ users. This compares self-reported patterns — not clinical head-to-head trials.

Last reviewed . By the PeptIQ team.

Observational reporting only — not medical advice. Does not recommend doses, protocols, or treatments.

LL-37

6 community reports

Overall experience

From check-in ratings — separate from side effects logged below. Side effects are logged separately from overall experience. A favorable check-in can still include nausea, fatigue, or injection-site reactions.

Favorable 100% · Mixed 0% · Unfavorable overall 0%

Most reported benefits

Benefits users selected when logging a favorable or mixed check-in.

Recovery
6

Self-reported dose per injection

Median bucket: 100–200 mcg · Most common: 100–200 mcg

Reports span 100–400 mcg

100–200
4
200–400
2

Anonymized self-reports from PeptIQ users — not prescribing guidance. Buckets group similar logged amounts; open-ended top buckets mean “at least” that dose.

Commonly stacked with

MK-677

24 community reports

Overall experience

From check-in ratings — separate from side effects logged below. Side effects are logged separately from overall experience. A favorable check-in can still include nausea, fatigue, or injection-site reactions.

Favorable 98% · Mixed 2% · Unfavorable overall 0%

Most reported benefits

Benefits users selected when logging a favorable or mixed check-in.

Sleep
135

Most logged side effects

Side effects are logged separately from overall experience. A favorable check-in can still include nausea, fatigue, or injection-site reactions.

Water retention
2
Fatigue
1

Self-reported dose per injection

Median bucket: 2+ mg · Most common: 2+ mg

Reports span 2 to ≥ 2 mg (open-ended top bucket)

2+ mg
135

Anonymized self-reports from PeptIQ users — not prescribing guidance. Buckets group similar logged amounts; open-ended top buckets mean “at least” that dose.

How repeat users are trending

Among repeat reporters, 91% said they felt similar to their last entry, 9% more positive, and 0% more negative.

Overall, repeat reporters leaned more positive than their previous entry.

Median gap between entries: 156 days · Based on 22 repeat reporters

Sources (10)

Published sources linked on the LL-37 and MK-677 wiki pages.

  1. PubMed

    LL-37, the only human member of the cathelicidin family of antimicrobial peptides

    Vandamme D, Landuyt B, Luyten W, et al. Biochim Biophys Acta. 2012

    Source
    Wiki study page →
  2. PubMed

    The antimicrobial peptide LL-37 inhibits biofilm formation

    Dean SN, Bishop BM, van Hoek ML. BMC Microbiol. 2011

    Source
    Wiki study page →
  3. PubMed

    Rosacea: Pathogenesis and Therapeutic Correlates

    Geng RSQ, Bourkas AN, Mufti A, et al. Journal of cutaneous medicine and surgery. 2024

    Source
    Wiki study page →
  4. PubMed

    LL-37 antimicrobial peptide: Molecular characterisation and its role in oral health and disease-A narrative review

    Soman D, P J, Cm M, et al. Archives of oral biology. 2026

    Source
    Wiki study page →
  5. PubMed

    MK-677, an orally active growth hormone secretagogue: effects on body composition

    Murphy MG, Plunkett LM, Gertz BJ, et al. J Clin Endocrinol Metab. 1998

    Source
    Wiki study page →
  6. PubMed

    Two-year treatment with ibutamoren increases bone mineral density, body composition, and quality of life

    Nass R, Pezzoli SS, Oliveri MC, et al. J Clin Endocrinol Metab. 2008

    Source
    Wiki study page →
  7. ClinicalTrials.gov

    Ibutamoren (MK-677) studies on ClinicalTrials.gov

    ClinicalTrials.gov. Clinical trial registry. 2024

    Source
    Wiki study page →
  8. PubMed

    MK-677, an orally active growth hormone secretagogue, reverses diet-induced catabolism

    Murphy MG, Plunkett LM, Gertz BJ, et al. The Journal of clinical endocrinology and metabolism. 1998

    Source
    Wiki study page →
  9. PubMed

    Characterization of growth hormone secretagogue small molecule ibutamoren (MK-0677) and its possible metabolites in thoroughbred horses for doping control

    Philip M, Karakka Kal AK, Subhahar MB, et al. Rapid communications in mass spectrometry : RCM. 2022

    Source
    Wiki study page →