Peptides researched for
Energy and fatigue
Steady energy through the day
3 peptides · 3 studies
What people research this for
Feeling tired all the time is one of the most common complaints there is. People want steady energy through the day without a crash. Peptide research on energy is early, and much of it looks at cells and animals.
Researched for
- Low energy
- Daytime fatigue
- Stamina
What the studies say so far
Most of this research studies how cells make energy, in the lab or in animals. The studies in people are small and short. Tiredness that will not go away has many possible causes, including poor sleep, low iron, and thyroid problems, so it is worth seeing a doctor. Nothing here has been proven to raise energy in healthy people.
Peptides studied
Each peptide below has been studied in this area. The label shows how far that research has gone.
MOTS-C
Early lab and animal researchAnimal study · 1 study
Study note. A 2021 paper studied MOTS-c and exercise capacity, mostly in mice of different ages.
- MOTS-c is an exercise-induced mitochondrial-encoded regulator of age-dependent physical decline and muscle homeostasis. (opens in a new tab)
Reynolds JC, Lai RW, Woodhead JST · Nature communications · 2021 · PubMed
- MOTS-c is an exercise-induced mitochondrial-encoded regulator of age-dependent physical decline and muscle homeostasis. (opens in a new tab)
SS-31
Small early studies in peopleRandomized trial in people · 1 study
Study note. A 2018 randomized trial studied elamipretide (SS-31) in adults with primary mitochondrial myopathy, a rare disease. It does not tell us about everyday fatigue.
- Randomized dose-escalation trial of elamipretide in adults with primary mitochondrial myopathy. (opens in a new tab)
Karaa A, Haas R, Goldstein A · Neurology · 2018 · PubMed
- Randomized dose-escalation trial of elamipretide in adults with primary mitochondrial myopathy. (opens in a new tab)
NAD+
Small early studies in peopleRandomized trial in people · 1 study
Study note. A 2018 randomized trial found that nicotinamide riboside, an oral NAD+ precursor, raised NAD+ in healthy middle-aged and older adults. It studied the precursor, not NAD+ injections.
- Chronic nicotinamide riboside supplementation is well-tolerated and elevates NAD(+) in healthy middle-aged and older adults. (opens in a new tab)
Martens CR, Denman BA, Mazzo MR · Nature communications · 2018 · PubMed
- Chronic nicotinamide riboside supplementation is well-tolerated and elevates NAD(+) in healthy middle-aged and older adults. (opens in a new tab)
Look this up in the PeptIQ app
The app has the same research and sources, next to the tools you use to track your own protocol.
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