Peptides researched for
Stroke / ischemic brain injury
Recovering after a stroke
2 peptides · 3 studies
What people research this for
After a stroke, people want to get back as much movement, speech, and independence as they can. Two peptides have been studied for brain injury after a stroke. Neither replaces emergency stroke care or rehab.
Researched for
- Recovery after a stroke
- Brain injury from lost blood flow
- Protecting brain cells
What the studies say so far
A Cochrane review, one of the most careful kinds of research summary, looked at Cerebrolysin for strokes caused by a blocked blood vessel. It found limited evidence and rated it low certainty. The Semax research here is in rats, where scientists tracked how immune and inflammation genes responded after blood flow to the brain was cut off. For most peptides, no benefit after a stroke has been shown in people.
Peptides studied
Each peptide below has been studied in this area. The label shows how far that research has gone.
Cerebrolysin
Mixed resultsResearch review · 1 study
Study note. Cochrane review of Cerebrolysin in acute ischemic stroke reports limited and low-certainty evidence.
- Cerebrolysin for acute ischaemic stroke. (opens in a new tab)
Ziganshina LE, Abakumova T, Vernay L · The Cochrane database of systematic reviews · 2017 · PubMed
- Cerebrolysin for acute ischaemic stroke. (opens in a new tab)
Semax
Early lab and animal researchAnimal study · 2 studies
Study note. ACTH-like / glyproline peptide papers map immune and inflammatory gene responses after experimental cerebral ischemia.
- Synthetic Adrenocorticotropic Peptides Modulate the Expression Pattern of Immune Genes in Rat Brain following the Early Post-Stroke Period. (opens in a new tab)
Filippenkov IB, Remizova JA, Stavchansky VV · Genes · 2023 · PubMed
- Insight into Glyproline Peptides' Activity through the Modulation of the Inflammatory and Neurosignaling Genetic Response Following Cerebral Ischemia-Reperfusion. (opens in a new tab)
Stavchansky VV, Filippenkov IB, Remizova JA · Genes · 2022 · PubMed
- Synthetic Adrenocorticotropic Peptides Modulate the Expression Pattern of Immune Genes in Rat Brain following the Early Post-Stroke Period. (opens in a new tab)
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