Peptides researched for
HIV-associated lipodystrophy / visceral fat
1 peptide · 4 studies
What people research this for
Some people living with HIV build up stubborn fat deep in the belly. They want to reduce it and protect their long-term health. Tesamorelin has FDA approval for this specific use, which makes it one of the better-studied peptides on this site.
Researched for
- Deep belly fat in people with HIV
- Body fat changes linked to HIV
- Liver and muscle health
What the studies say so far
Tesamorelin is FDA approved for excess belly fat in people with HIV. Randomized trials found it reduced the deep fat around the organs. Follow-up analyses linked that fat loss to better liver blood tests, less fat inside muscle, and more muscle area on scans. A clinician prescribes and supervises it. The results apply to people with HIV and do not tell us what happens in anyone else.
Peptides studied
Each peptide below has been studied in this area. The label shows how far that research has gone.
Tesamorelin
Tested in clinical trialsRandomized trial in people · 4 studies
Study note. FDA-labeled GHRH analog for excess abdominal fat in HIV; peer-reviewed work shows VAT reduction plus muscle-area and liver-enzyme associations.
- EGRIFTA (tesamorelin) for injection - Prescribing Information (opens in a new tab)
Theratechnologies · FDA Drug Label · 2010 · FDA label
- The Growth Hormone Releasing Hormone Analogue, Tesamorelin, Decreases Muscle Fat and Increases Muscle Area in Adults with HIV. (opens in a new tab)
Adrian S, Scherzinger A, Sanyal A · The Journal of frailty & aging · 2019 · PubMed
- Visceral fat reduction with tesamorelin is associated with improved liver enzymes in HIV. (opens in a new tab)
Fourman LT, Czerwonka N, Feldpausch MN · AIDS (London, England) · 2017 · PubMed
- Tesamorelin improves fat quality independent of changes in fat quantity. (opens in a new tab)
Lake JE, La K, Erlandson KM · AIDS (London, England) · 2021 · PubMed
- EGRIFTA (tesamorelin) for injection - Prescribing Information (opens in a new tab)
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