PubMed
Follistatin induces muscle hypertrophy through satellite cell proliferation and inhibition of both myostatin and activin
Winbanks et al., 2009
Healing & RecoveryResearch Only — Extreme CautionB
Follistatin 344
FST344 / Myostatin Inhibitor
Follistatin 344 is an isoform of follistatin (FST), a naturally occurring glycoprotein that binds and neutralizes TGF-β superfamily members, most notably myostatin (GDF-8) and activin A. Animal studies show dramatic and permanent muscle hypertrophy with single gene therapy doses. Human pharmacokinetic and safety data are extremely limited; the risk of irreversible muscular hypertrophy and unknown off-target effects make this highly experimental. Research only — extreme caution advised.
Observational report only — live community data. Not medical advice. Does not recommend doses, protocols, or treatments.
- Studies cited
- 6
- Research grade
- B
- Experience
- 100
- Activity
- 83
Overall check-ins
Trackers & reports
Overview
About Follistatin 344
Follistatin 344 is an isoform of follistatin (FST), a naturally occurring glycoprotein that binds and neutralizes TGF-β superfamily members, most notably myostatin (GDF-8) and activin A. Animal studies show dramatic and permanent muscle hypertrophy with single gene therapy doses. Human pharmacokinetic and safety data are extremely limited; the risk of irreversible muscular hypertrophy and unknown off-target effects make this highly experimental. Research only — extreme caution advised.
- Category
- Healing & Recovery
- Regulatory status
- Research Only — Extreme Caution
- Also known as
- FST344 / Myostatin Inhibitor
- Self-reports
- 6
Community
What 6 users report
6 community reports
Overall experience
From check-in ratings — separate from side effects logged below. Side effects are logged separately from overall experience. A favorable check-in can still include nausea, fatigue, or injection-site reactions.
Favorable 100% · Mixed 0% · Unfavorable overall 0%
Most reported benefits
Benefits users selected when logging a favorable or mixed check-in.
Recovery
6
Sleep
6
Energy
3
Self-reported dose per injection
Median bucket: 50–100 mcg · Most common: 50–100 mcg
Reports span 50–200 mcg
50–100
4
100–200
2
Anonymized self-reports from PeptIQ users — not prescribing guidance. Buckets group similar logged amounts; open-ended top buckets mean “at least” that dose.
Commonly stacked with
Research
Cited research (5)
Source
ClinicalTrials.gov
Follistatin / Myostatin inhibition studies on ClinicalTrials.gov
ClinicalTrials.gov, 2024
PubMed
Follistatin-derived peptide expression in muscle decreases adipose tissue mass and prevents hepatic steatosis
Sugiyama et al., 2010
PubMed
Evaluation of follistatin as a therapeutic in models of skeletal muscle atrophy associated with denervation and tenotomy
Sepulveda et al., 2015
PubMed
The impact of weight loss on fat-free mass, muscle, bone and hematopoiesis health: Implications for emerging pharmacotherapies aiming at fat reduction and lean mass preservation
Stefanakis et al., 2024
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Frequently asked
What do PeptIQ users report about Follistatin 344?
This page summarizes 6 anonymized self-reports from PeptIQ users who track Follistatin 344, including commonly reported effects and co-tracked peptides. These are observational patterns, not clinical outcomes.
How do side effects relate to overall experience for Follistatin 344?
PeptIQ separates overall check-in ratings (favorable, mixed, or unfavorable) from logged side effects like nausea or fatigue. Users often report benefits and side effects in the same check-in — a high experience score does not mean zero side effects were noted.
What research is cited for Follistatin 344?
5 sources are linked on this page, including PubMed articles, clinical trial registries, and FDA labels where applicable. Citations describe published research — not recommendations.
Is Follistatin 344 safe to use?
This wiki does not assess safety or recommend use. Follistatin 344 is listed as Research Only — Extreme Caution. Consult a licensed clinician for personal medical decisions.
What are the purported benefits and uses of Follistatin 344?
This wiki summarizes observational community reports and linked citations for Follistatin 344. It does not assert therapeutic benefits. See the cited research list on this page and the educational profile for Follistatin 344 for study-level context — not medical advice.
What is the legal status of Follistatin 344?
Follistatin 344 is listed in PeptIQ as Research Only — Extreme Caution. Regulatory status varies by jurisdiction and can change. This wiki does not provide legal advice; check current FDA and local rules and talk with a licensed clinician or counsel for personal decisions.
What are the known or theoretical side effects and risks of Follistatin 344?
Safety data quality for Follistatin 344 varies widely by compound and study design. PeptIQ does not establish a risk profile here. Review primary literature, product labeling where applicable, and clinician guidance. Community self-reports are not a substitute for clinical evidence.
What is the current state of research on Follistatin 344?
This page links 5 indexed sources for Follistatin 344. Evidence maturity differs by application — some peptides have large human programs, others are mostly preclinical. Treat citation counts as literature volume, not proof of efficacy.