PubMed
An NNMT inhibitor activates oxidative metabolism and reduces obesity in mice
Neelakantan et al., 2019
NNMT Inhibitor
Small-molecule NNMT inhibitor often discussed with metabolic protocols; investigational.
Trend index
Overview
Small-molecule NNMT inhibitor often discussed with metabolic protocols; investigational.
Community
Positive 94% · Neutral 6% · Negative 0%
Median: 2000+ mcg · Most common: 2000+ mcg
Among repeat reporters, 86% said they felt similar to their last entry, 14% more positive, and 0% more negative.
Overall, repeat reporters leaned more positive than their previous entry.
Median gap between entries: 86 days · Based on 28 repeat reporters
Research
PubMed
Neelakantan et al., 2019
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This page summarizes 43 anonymized self-reports from PeptIQ users who track 5-Amino-1MQ, including commonly reported effects and co-tracked peptides. These are observational patterns, not clinical outcomes.
1 sources are linked on this page, including PubMed articles, clinical trial registries, and FDA labels where applicable. Citations describe published research — not recommendations.
This wiki does not assess safety or recommend use. 5-Amino-1MQ is listed as Research Only. Consult a licensed clinician for personal medical decisions.
Research, primarily in animal models, suggests 5-Amino-1MQ may have a wide range of therapeutic potentials due to its ability to promote angiogenesis (formation of new blood vessels), stimulate collagen synthesis, and modulate inflammatory responses.
Source5-Amino-1MQ is not approved by the FDA for any human use. There is no legal basis for selling it as a drug, food, or dietary supplement in the United States. The FDA has classified 5-Amino-1MQ as a Category 2 bulk drug substance, which explicitly prohibits licensed compounding pharmacies from using it in compounded medications.
SourceThe safety and effectiveness of 5-Amino-1MQ have not been thoroughly evaluated in humans through rigorous clinical trials. This lack of human data means that safe dosages, short-term side effects, and long-term health consequences are largely unknown.
SourceWhile there are over 200 published studies on 5-Amino-1MQ, the vast majority are animal or in vitro (cell) studies. These preclinical studies consistently show positive results across various tissue types. However, there is a significant lack of comprehensive human clinical trial data.
Source