PubMed
Selank and short peptides regulate expression of inflammatory genes
Ershov et al., 2017
Tuftsin Analog TP-7
Selank is a synthetic heptapeptide anxiolytic based on the immunomodulatory peptide tuftsin (Thr-Lys-Pro-Arg), developed and approved in Russia for generalized anxiety disorder and as an immunomodulator. It demonstrates anxiolytic and nootropic effects comparable to benzodiazepines but without the sedation, dependence potential, or memory impairment. Administered intranasally. Not FDA-approved in the US.
Trend index
Overview
Selank is a synthetic heptapeptide anxiolytic based on the immunomodulatory peptide tuftsin (Thr-Lys-Pro-Arg), developed and approved in Russia for generalized anxiety disorder and as an immunomodulator. It demonstrates anxiolytic and nootropic effects comparable to benzodiazepines but without the sedation, dependence potential, or memory impairment. Administered intranasally. Not FDA-approved in the US.
Community
Positive 3% · Neutral 97% · Negative 0%
Median: 200–400 mcg · Most common: 200–400 mcg
Among repeat reporters, 86% said they felt similar to their last entry, 14% more positive, and 0% more negative.
Overall, repeat reporters leaned more positive than their previous entry.
Median gap between entries: 54 days · Based on 35 repeat reporters
Research
PubMed
Ershov et al., 2017
PubMed
Seredenin et al., 2008
PubMed
Ershov et al., 2010
Help
This page summarizes 57 anonymized self-reports from PeptIQ users who track Selank, including commonly reported effects and co-tracked peptides. These are observational patterns, not clinical outcomes.
3 sources are linked on this page, including PubMed articles, clinical trial registries, and FDA labels where applicable. Citations describe published research — not recommendations.
This wiki does not assess safety or recommend use. Selank is listed as Intl. Approved (Russia). Consult a licensed clinician for personal medical decisions.
Research, primarily in animal models, suggests Selank may have a wide range of therapeutic potentials due to its ability to promote angiogenesis (formation of new blood vessels), stimulate collagen synthesis, and modulate inflammatory responses.
SourceSelank is not approved by the FDA for any human use. There is no legal basis for selling it as a drug, food, or dietary supplement in the United States. The FDA has classified Selank as a Category 2 bulk drug substance, which explicitly prohibits licensed compounding pharmacies from using it in compounded medications.
SourceThe safety and effectiveness of Selank have not been thoroughly evaluated in humans through rigorous clinical trials. This lack of human data means that safe dosages, short-term side effects, and long-term health consequences are largely unknown.
SourceWhile there are over 200 published studies on Selank, the vast majority are animal or in vitro (cell) studies. These preclinical studies consistently show positive results across various tissue types. However, there is a significant lack of comprehensive human clinical trial data.
Source