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Bacteriostatic Water for Peptides: Complete Guide to BAC Water

Everything you need to know about bacteriostatic water for peptide reconstitution. Learn what it is, how to use it, storage guidelines, and alternatives.

Michael Torres
Clinical Pharmacist
Bacteriostatic Water for Peptides: Complete Guide to BAC Water

What is Bacteriostatic Water?

Bacteriostatic water (BAC water) is sterile water that contains 0.9% benzyl alcohol as a preservative. This preservative inhibits bacterial growth, making it safe for multiple uses from the same vial.

Key Characteristics

  • Composition: Sterile water + 0.9% benzyl alcohol
  • pH: Near neutral (approximately 4.5-7.0)
  • Preservative action: Bacteriostatic (stops growth), not bactericidal (kills)
  • Multi-use: Safe for multiple withdrawals
  • Why BAC Water for Peptides?

    The Multi-Dose Problem

    Peptide vials are typically used multiple times:

  • A 5mg vial might provide 20+ doses
  • Each withdrawal introduces potential contamination
  • Without preservative, bacteria can multiply
  • How BAC Water Protects

  • Benzyl alcohol prevents bacterial reproduction
  • Solution remains safe throughout use period
  • Extends practical vial life to 28+ days
  • BAC Water vs. Alternatives

    Comparison Chart

    When to Use Each

    Bacteriostatic Water:

  • Standard choice for peptide reconstitution
  • Multiple doses from one vial
  • Sterile Water:

  • Single-use situations only
  • Benzyl alcohol sensitivity
  • Must discard after opening
  • How to Use BAC Water

    Storage Before Opening

  • Room temperature (59-86°F / 15-30°C)
  • Protected from light
  • Check expiration date
  • Inspect for cloudiness/particles
  • Reconstitution Process

  • Remove caps from both vials
  • Wipe rubber stoppers with alcohol
  • Draw desired BAC water amount
  • Inject slowly into peptide vial
  • Allow to dissolve (don't shake)
  • Store reconstituted peptide properly
  • After Opening BAC Water

  • Store at room temperature or refrigerated
  • Use within 28 days of opening
  • Mark opening date on vial
  • Inspect before each use
  • Common Questions Answered

    How Much BAC Water Should I Use?

    This depends on desired concentration:

    Pro tip: Use PeptIQ's calculator for exact measurements.

    Does BAC Water Damage Peptides?

    No, when used properly:

  • Benzyl alcohol concentration is low
  • Peptides remain stable
  • Millions of doses used safely
  • Can I Make My Own BAC Water?

    Not recommended:

  • Sterility is critical
  • Precise concentration matters
  • Commercial products are reliable and inexpensive
  • Risk of contamination is too high
  • Storage Guidelines

    Unopened BAC Water

    Opened BAC Water

    Reconstituted Peptides

    Water TypePreservativeMulti-UseBest For
    BacteriostaticYes (benzyl alcohol)YesMulti-dose peptides
    Sterile WaterNoSingle use onlyIV medications
    Sodium Chloride 0.9%NoSingle useSome medications
    BAC SalineYesYesSome applications
    Peptide AmountBAC WaterConcentration
    5mg1mL5mg/mL
    5mg2mL2.5mg/mL
    5mg2.5mL2mg/mL
    10mg2mL5mg/mL
    ConditionDuration
    Room temperatureUntil expiration
    RefrigeratedUntil expiration
    ConditionDuration
    Room temperature28 days
    Refrigerated28 days
    ConditionDuration
    Refrigerated28-42 days (peptide dependent)
    Room temperatureUse immediately or discard

    Quality Considerations

    What to Look For

  • USP grade designation
  • Clear, colorless solution
  • Sealed properly
  • Valid expiration date
  • Reputable supplier
  • Red Flags

    ⚠️ Unusual color or cloudiness

    ⚠️ Particles visible

    ⚠️ Damaged seal

    ⚠️ Unknown source

    ⚠️ Past expiration

    Benzyl Alcohol Sensitivity

    Who Should Avoid

  • Neonates (infants)
  • Those with known sensitivity
  • When directed by healthcare provider
  • Alternatives if Sensitive

  • Sterile water (single use only)
  • Reconstitute smaller amounts more frequently
  • Consult healthcare provider for options

Frequently Asked Questions

Q: Can I use regular water?

A: Never. Tap water contains microorganisms and minerals that can damage peptides and cause infection.

Q: How long does BAC water last in a vial?

A: 28 days after opening, regardless of refrigeration.

Q: Is it okay if BAC water is slightly yellow?

A: No. It should be completely clear and colorless. Discard if discolored.

Q: Can I refrigerate unopened BAC water?

A: Yes, but room temperature is fine. Either is acceptable.

Q: Do I need a prescription for BAC water?

A: In most jurisdictions, no. It's available at many pharmacies and online.

Conclusion

Bacteriostatic water is an essential supply for anyone using peptides. Its preservative properties allow safe multi-dose use, making it the standard choice for peptide reconstitution. Always use quality products, store properly, and track your opening dates for safety.

#bacteriostatic water#reconstitution#BAC water#sterile water#peptide preparation
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